Organometallics in Flow

• Save time, money and energy with our flexible, scalable and patented technology
• Accelerate your time-to-market and gain access to the full class of organometallics and multiple follow-up reactions
• Easily manage high exothermicities, metal activation and side product formation and decrease your safety concerns

What are the main advantages over conventional processing?

The main advantages of the scalable continuous organometallic reagent synthesis are the increase in safety due to small reactor volumes, improved product quality due to the process window it operates in, and flexible production of exactly the amount of reagent needed and required.

What throughputs are currently obtainable?

The largest set-up in existence has processed organometallic solutions with up to 18 L/h. The maximum throughputs achievable for a specific organometallic reagent is mainly due to its concentration and reactivity.

How do you minimize unwanted side reactions?

Unwanted side reactions and here particularly Wurtz coupling are suppressed through the use of a large metal excess, very short residence times in the range of only a few minutes and narrow residence time distributions.

Is it a true continuous process in both feeds?

The liquid halide solution is fed from the bottom to the top through the reactor, while the metal is also continuously replenished within the reactor to maintain the large metal access crucial for improved product quality, rendering the operation truly continuous in liquid as well as solid feed.